Status Report from SPAUD Part 2

Part 2: Perspectives on Antibiotic Use and the Microbiome and Review of Microbiologic Effects of Selected Specific Therapeutic Agents Commonly Used by Dermatologists


Abstract

Status Report from SPAUD Part 2
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In this second part of a three-part series addressing several issues related to antibiotic use in dermatology, potential effects of antibiotic use on the human microbiota and microbiome are reviewed. Data from available literature on the microbiologic effects of specific therapeutic agents commonly used in dermatology, including oral isotretinoin, tetracycline agents, and sub-antimicrobial (sub-antibiotic) dose doxycycline, are also discussed. (J Clin Aesthet Dermatol. 2016;9(5):11–17.)

In Part 1 of this three-part article series, antibiotic exposure, prescribing patterns, and clinical sequelae of antibiotic consumption were discussed. The information gleaned from available literature and from the perspectives of professionals with knowledge and strong interest in this area will hopefully guide clinicians in using antibiotics more judiciously and responsibly.

In this second part of the series, potential effects of antibiotic use on the human microbiome are discussed along with data on oral isotretinoin, subantimicrobial (sub-antibiotic) dose doxycycline, and other therapeutic agents commonly used in dermatology.

aJames Q. Del Rosso, DO; bRichard L. Gallo, MD, PhD; cDiane Thiboutot, MD; dGuy F. Webster, MD; eTed Rosen, MD; fJames J. Leyden, MD; gClay Walker, PhD; hGeorge Zhanel, PhD; iLawrence Eichenfield, MD aDermatology Adjunct Faculty, Touro University Nevada, Henderson, Nevada; bDepartment of Dermatology, University of California San Diego, San Diego, California; cDepartment of Dermatology, Penn State University, Hershey, Pennsylvania; dDepartment of Dermatology, Jefferson Medical College, Philadelphia, Pennsylvania; eDepartment of Dermatology, Baylor College of Medicine, Houston, Texas; fDepartment of Dermatology, University of Pennsylvania, Philadelphia, Pennsylvania; gUniversity of Florida College of Dentistry, Gainesville, Florida; hDepartment of Medical Microbiology and Infectious Diseases, University of Manitoba, Winnipeg, Canada; iDepartment of Dermatology (Pediatrics), University of California San Diego, San Diego, California

Click here to read more: http://www.jcadonline.com/status-report-from-the-scientific-panel-on-antibiotic-use-in-dermatology-of-the-american-acne-and-rosacea-society-part-2-perspectives-on-antibiotic-use-and-the-microbiome-and-review-of-microbiologic/

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Scientific Panel on Antibiotic Use in Dermatology - Status Report

Scientific Panel on Antibiotic Use in Dermatology Meeting Info

Part 1: Antibiotic Prescribing Patterns, Sources of Antibiotic Exposure, Antibiotic Consumption and Emergence of Antibiotic Resistance, Impact of Alterations in Antibiotic Prescribing, and Clinical Sequelae of Antibiotic Use

Part 2: Perspectives on Antibiotic Use and the Microbiome and Review of Microbiologic Effects of Selected Specific Therapeutic Agents Commonly Used by Dermatologists

Part 3: Current Perspectives on Skin and Soft Tissue Infections with Emphasis on Methicillin-resistant Staphylococcus aureus, Commonly Encountered Scenarios when Antibiotic Use May Not Be Needed, and Concluding Remarks on Rational Use of Antibiotics in Dermatology