September 1, 2019 Issue

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Hot Topics at a Glance

Industry News

  • Cassiopea announces FDA submission of new drug application for Clascoterone cream 1%, the first new mechanism of action for acne in nearly 40 years. 
  • Almirall issues call for grant submissions for development of new immunodermatology therapies. 

New Medical Research

  • Efficacy of 30% azelaic acid peel in the nonpharmacological treatment of facial acne. 
  • The clinical efficacy of ReCell® autologous cell regeneration techniques combined with dermabrasion treatment in acne scars. 
  • Clinical efficacy of herbal extracts in treatment of mild to moderate acne vulgaris: A 8-week, double-blinded, randomized, controlled trial.
  • Fractional Erbium-YAG laser and platelet-rich plasma as single or combined treatment for atrophic acne scars: A randomized clinical trial. 
  • Evaluation of PSP technique including dot peeling, subcision and intradermal injection of PRP in the treatment of atrophic post-acne scars. 
  • A cross-sectional study of rosacea and risk factors in women with frontal fibrosing alopecia. 
  • Intralesional corticosteroid injection for the treatment of hidradenitis suppurativa: A multicentre retrospective clinical study.
  • Multimodal clinical imaging assessment of the outcome in mild-to-moderate acne: A prospective study.

Clinical Reviews

  • The frequency of off-label prescribing in the treatment of dermatologic disease. 
  • A systematic review of factors influencing treatment adherence in chronic inflammatory skin disease - strategies for optimizing treatment outcome. 
  • Promising plant-derived secondary metabolites for treatment of acne vulgaris: A mechanistic review. 
  • PAPA and FMF in two siblings: Possible amplification of clinical presentation? A case report. 
  • Hyperhidrosis affects quality of life in hidradenitis suppurativa: A prospective analysis. 
  • Hidradenitis suppurativa: Current understanding, diagnostic and surgical challenges, and developments in ultrasound application. 
  • The effects of isotretinoin therapy on serum homocysteine, folate and vitamin B12 levels in patients with acne: A meta-analysis and meta-regression. 
  • SAPHO syndrome of the temporomandibular joint associated with trismus: A case report and review of the literature. 
  • Onychocryptosis and asymptomatic external urethritis as complications of oral isotretinoin therapy. 
  • The role of IL-17 in papulopustular rosacea and future directions. 
  • Targeting the gut-skin axis - probiotics as new tools for skin disorder management? 
  • Consumer safety considerations of skin and oral microbiome perturbation. 
  • Synovitis, acne, pustulosis, hyperostosis, and osteitis (SAPHO) syndrome with destructive spondylitis: A case report. 
  • Acne treatment alternatives to know.


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