January 15, 2020 Issue

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Hot Topics at a Glance

AARS Announcements

  • Call for AARS Clinical Research Award Applications
  • Register Now for Our 15th Annual AARS Networking Reception

Industry News

  • FDA approves Ortho Dermatologics’ Arazlotm (tazarotene) lotion, 0.045%, for acne vulgaris.

New Medical Research

  • Analysis of characteristics and trends in treatment response of hidradenitis suppurativa patients: A southern US cohort study.
  • Clinical pharmacokinetics, safety and exploratory efficacy study of a topical bactericidal VB-1953: Analysis of single and multiple doses in a Phase I trial in acne vulgaris subjects.
  • Rifampin-moxifloxacin-metronidazole combination therapy for severe Hurley Stage 1 hidradenitis Suppurativa: prospective short-term trial and one-year follow-up in 28 consecutive patients.
  • A split-face comparative study to evaluate the efficacy of 50% pyruvic acid against a mixture of glycolic and salicylic acids in the treatment of acne vulgaris.
  • Efficacy and safety of artemether emulsion for the treatment of mild-to-moderate acne vulgaris: A randomized pilot study.
  • Development and investigation of vitamin c-enriched adapalene-loaded transfersome gel: A collegial approach for the treatment of acne vulgaris.
  • A multicenter, randomized, double-masked, parallel group, vehicle-controlled phase 2b study to evaluate the safety and efficacy of 1% and 3% topical minocycline gel in patients with papulopustular rosacea.
  • Hydroxychloroquine is a novel therapeutic approach for rosacea.
  • Antimicrobial activity of certain natural-based plant oils against the antibiotic-resistant acne bacteria.
  • Nd:YAG laser vs IPL in inflammatory and noninflammatory acne lesion treatment.
  • Demodex infestation in patients with rosacea.
  • Clinical response rates, placebo response rates and significantly associated covariates are dependent upon choice of outcome measure in hidradenitis suppurativa: A post-hoc analysis of PIONEER 1 and 2 individual patient data.
  • Alterations in innate immunity and epithelial cell differentiation are the molecular pillars of hidradenitis suppurativa.
  • Tretinoin 0.05% lotion for the once-daily treatment of moderate and severe acne vulgaris in females: Effect of age on efficacy and tolerability.
  • The fate of active acne and acne scars following treatment with fractional radiofrequency.
  • Pilonidal sinus disease: An intergluteal localization of hidradenitis suppurativa/acne inversa: A cross-sectional study among 2465 patients.
  • Development of a new patient-reported outcome measure to evaluate treatments for acne and acne scarring: The ACNE-Q.
  • Atrophic acne scar: A process from altered metabolism of elastic fibres and collagen fibres based on transforming growth factor-β1 signaling.

Clinical Reviews

  • Update on the use of dapsone in dermatology.
  • Skin immunity and its dysregulation in atopic dermatitis, hidradenitis suppurativa and vitiligo.
  • Hidradenitis suppurativa: infection, autoimmunity, or both? 
  • Rosacea: a wholistic review and update from pathogenesis to diagnosis and therapy.
  • Efficacy of topical ivermectin and impact on quality of life in patients with papulopustular rosacea: A systematic review and meta-analysis.
  • 5-Aminolevulinic acid photodynamic therapy and isotretinoin for treatment of drug-induced acne fulminans in a patient with idiopathic thrombocytopenic purpura.
  • Truncal acne: A neglected entity.

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