AARS Hot Topics

Throughout the year, the AARS distributes updates in the fields of acne and rosacea, that announce pertinent clinical research findings or updates in acne and rosacea treatments or pathogenesis, and keep you informed of educational events or initiatives supported by AARS.  See below for the most recent AARS update, and visit the archive of previous AARS Hot Topics

 

Acne Priority Setting Top Ten Research Questions Revealed

After over a year of gathering survey results and narrowing down suggested areas of research, the Acne Priority Setting Partnership (PSP) Organization has revealed the Top Ten research priorities in acne!  On March 4, 2014, a group of 24 patients and health care professionals determined the questions they felt were most important to address through research. 

 

The top five questions were:

1. What management strategy should be adopted for the treatment of acne in order to optimize short and long-term outcomes? 

2. What is the correct way to use antibiotics in acne to achieve the best outcomes with least risk?

3. What is the best treatment for acne scars?

4. What is the best way of preventing acne?

5. What is the correct way to use oral isotretinoin (Roaccutane) in acne in order to achieve the best outcomes with the least risk of potentially serious adverse effects?

 

Click over to the Acne PSP website to see the complete list.

On behalf of the Acne PSP Organization, AARS would like to thank all those who contributed to this important initiative!

 

AARS Update February 2014

Acne Core Outcome Research Network (ACORN)

A major question facing dermatologists and other providers is how do acne treatments compare to each other?  In today's economic decline, it's not possible to conduct head-to-head trials of available acne medications in order to gather these important comparative data.  Statistical analysis of available trial data can be done using meta analysis, but the quality of these analyses relies on consistency in how the acne was evaluated in each trial, or, in other words, consistency in the outcome measure for acne.

 

In 2011, the National Institute of Arthritis, Musculoskeletal and Skin Diseases (NIAMS) had a call for grant applications to develop standardized outcome measures for clinical trials in skin diseases.  This served as an opportunity for an international group of dermatology clinicians and researchers with a long-standing interest in acne to combine their efforts and form the Acne Core Outcomes Research Network (ACORN).  The overarching goal of ACORN is to develop improved outcome measures of acne for use in clinical trials.  It is hoped that once the outcome measures are developed and validated that they may be adopted by the research community; thus allowing for generation of data that will facilitate comparison of acne treatments that in turn can help guide treatment decisions. 

 

In July 2013, we received the good news that the ACORN project would be funded by a cooperative research agreement with NIAMS.  We are establishing a scientific advisory board, seeking additional members to our network, establishing industry partnerships and developing a web-site where you can learn more about our group's efforts.  

 

The Acne Core Outcomes Research Network consists of international teams headed by Drs. Alison Layton and Anne Eady at Harrogate in the United Kingdom, Dr. Jerry Tan and Marc Frey in Windsor, Canada, and Dr. Diane Thiboutot at the Pennsylvania State University in the United States.  Dr. Meg Chren from UCSF lends her expertise in development and evaluation of quality of life measures.  We have assembled a group of statisticians with expertise in analysis of clinical trial data and quality of life measures and a librarian to assist the group with systematic reviews.  Canfield Scientific is our first industry partner and will be collaborating with ACORN on assessing novel technologies for acne lesion counting.  Moving forward, we hope to engage more providers, patients and industry partners in our efforts to improve the study of acne.  

 

The ACORN is funded by a cooperative research agreement with NIH.  Click here to see more information about ACORN and check the AARS website for future updates from our leadership on this exciting initiative!